Jama

Articoli pubblicati su jama

1. JAMA

2. Audio Highlights February 8-14, 2025

   Listen to the JAMA Editor’s Summary for an overview and discussion of the important articles appearing in JAMA.

3. Error in Table

   The Original Investigation titled “Assessment of Antitachycardia Pacing in Primary Prevention Patients: The APPRAISE ATP Randomized Clinical Trial,” published on October 3, 2024, was corrected to fix spelling errors in 2 nonauthor collaborators listed in Supplement 3. This article was corrected online.

4. Incorrect Author Name

   In the Original Investigation titled “Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury: the TRAIN Randomized Clinical Trial,” published in the November 19, 2024, issue of JAMA, an author name was incorrect. Carla Rynkowski Bittencourt should have appeared as Carla Bittencourt Rynkowski. This article was corrected online.

5. Book Notice

   Arrowsmith. By Sinclair Lewis. Cloth. Price, $2, net. Pp., 448. New York: Harcourt, Brace & Co., 1925.

6. Patient Information: Peptic Ulcer Disease

   This JAMA Patient Page describes peptic ulcers and their causes, signs and symptoms, diagnosis, and treatment options.

7. When You Drew the Graph

   of expected recovery and the asymptotic line that planed out flat enough to rest my head on and made a big fat dot there I wanted nothing more than to crawl out of my skin and so I did I left my body standing there hands clenched, on autopilot and I went anywhere else I went to our first date the night of our honeymoon our first house I floated out of the room because we had come so far just to get here just to have the privilege of your opinion because I didn’t understand how one person’s marathon could be such a failure in someone else’s eyes

8. Secret Part-Time

   In this narrative medicine essay, an internal medicine physician caught in the grind of academic practice considers a path of resistance through what is called secret part-time—altering one’s schedule quietly for personal matters.

9. Statins for Primary Prevention of Cardiovascular Disease

   To the Editor A recent study reported that utilizing the Predicting Risk of cardiovascular disease EVENTs (PREVENT) equations, developed by the American Heart Association (AHA) and American College of Cardiology (ACC), for calculating cardiovascular risk, would lead to millions fewer US residents at low risk of heart disease being recommended statins.

10. Statins for Primary Prevention of Cardiovascular Disease—Reply

    In Reply Development of a new cardiovascular risk equation has prompted reconsideration of the appropriate thresholds at which to recommend preventive therapy. In response, Dr Demasi and colleagues argue that lowering the risk threshold for statins would increase adverse effects, such as myalgias, but not help patients live longer or better.

11. Statins for Primary Prevention of Cardiovascular Disease—Reply

    In Reply We thank Dr Demasi and colleagues for sharing their perspectives. We judge that the statements we made are supported by the evidence and we stand by the rationale presented and the conclusions expressed in our Viewpoint. As we discussed, data from randomized clinical trials show net benefit of statin therapy for patient groups with 10-year major cardiovascular event rates as low as 3%. The new PREVENT risk equations from the AHA, which are substantially more precise and accurate for contemporary patient samples than prior equations, allow consideration of such lower thresholds for treatment initiation, with the potential of preventing many cardiovascular events.

12. Over Breakfast

    Says she’s doing okay Says she was nervous before last Friday’s appointment Says her daughter had to slow her down Says her daughter was like, Mom, Whoa, one thing at once Says it was cute Says the Golden Gate Bridge Looked so beautiful entering the city Says the ocean, the fog Says her doctor is her guide Says she has to put her complete trust in him Says that’s scary Says he said she’s doing well Says he said he’s happy with her progress Says he’s very cautious About saying more than that Says he doesn’t like to jump too far ahead Says again that he’s her guide Says they talked about what to expect next Says more pills Says adverse reactions Says insurance Says emptiness Says healing is here In the present moment, in living today Says she’s choosing what to hold And what to release Says she’s got no other choice All of us, I say She nods And aren’t these oranges delicious?

13. Delicious Oranges—Mental Health, Poetry, and the Non Sequitur

    Poetry, because of its mutability on the page, is a fascinating medium for simulating the dialogues we have that reflect our mental states. The non sequitur, although not a specifically poetic writing device, is often exploited especially effectively in verse to evoke the restless mind via its jumpy enjambment and juxtaposition. This emotion-mirroring capacity of poetry is perhaps why it is frequently used in therapeutic writing settings, such as poetry therapy and journaling. In “Over Breakfast,” we see the anxious mind at work in conversation—or perhaps more of a dramatic monologue—between 2 friends meeting in the wake of one’s recent cancer diagnosis. The rapid-fire, largely unpunctuated lines, most of which are initiated by “Says,” convey the agitation the speaker’s friend contends with as she narrates a response to her threatened health—with the second line “Says she was nervous before last Friday’s appointment” actually making it explicit. The breathless insistence on speaking, and the repetition itself, feel like an attempt by both interlocutors to manage the anxiety. The scatterbrained asides, from the daughter’s sternly telling her mother to slow down to the Golden Gate Bridge to “Says insurance/Says emptiness,” only heighten the sense of the friend’s disconnection and volatile mood. Yet the stunning turn of the final line, perhaps the most blatant and ironic non sequitur of the entire poem, dramatically underscores that all the distractions and jitteriness are ultimately a grasping at peace, and hope, amidst inchoate fears.

14. US Ranks Highest in Global Overdose Deaths

    A recent Commonwealth Fund report confirmed that the US overdose death rate remains far higher than in any other country. In 2022, the US overdose rate was 324 deaths per 1 million people, 1.5 times greater than in Scotland, the second-ranked nation with 219 deaths per million people. Although Scotland saw fewer deaths in 2022 than in previous years, rates in the US continued to climb, up about 53% from 2019. For the third consecutive year, drug overdoses claimed more than 100 000 lives in the US, according to provisional 2023 data from the US Centers for Disease Control and Prevention.

15. Permanent Contraception Procedures Increase Among Young Adults Post Dobbs

    More young adults in the US are undergoing tubal sterilization and vasectomy procedures in the wake of the Dobbs v Jackson Women’s Health Organization decision, with more substantial increases in states likely to ban abortion.

16. Systematic Review Examines GLP-1s Drugs’ Effectiveness and Safety in Patients Without Diabetes

    A systematic review of randomized clinical trials involving about 15 500 participants without diabetes found that all 12 of the identified glucagon-like peptide-1 (GLP-1) receptor agonists led to decreased body mass, waist circumference, and blood pressure. Of the 3 commercially available agents—liraglutide, semaglutide, and tirzepatide—the latter resulted in the greatest weight loss, with participants reporting up to an 18% change in body weight after nearly 17 months.

17. Global Study Reveals High Rates of Sexual Violence Against Children

    Sexual violence against children has profound and lasting consequences, including psychiatric disorders, substance use, sexually transmitted infections, unwanted pregnancies, and suicide risk. New global survey data revealed that more than 1 in 10 children aged 19 years or younger experienced sexual harassment—a form of sexual violence not involving contact, according to the World Health Organization—in their lifetime, which sheds new light on the prevalence of this public health issue.

18. Dementia Cases Expected to Nearly Double in the US by 2060

    A recent study estimated that the number of adults diagnosed with dementia each year in the US is expected to nearly double over the next 40 years, from 514 000 in 2020 to approximately 1 million by 2060. Researchers also estimate that after the age of 55 years, the current lifetime risk of dementia is 42%. That risk could reach 60% for specific demographics.

19. Which Digital Health Technologies Do Older Adults Use?

    This Medical News article is an interview with Cornelius A. James, MD, of the University of Michigan Medical School about his recent research examining the use of digital health technologies, including patient portals, among older US adults and how it relates to his own experience in the clinic.

20. A New Call for US Alcohol Labels to Warn of Cancer Link

    This Medical News article discusses updating health warning labels on alcoholic beverages to include the fact that drinking alcohol causes certain cancers, with examples of initiatives in Canada, Ireland, and South Korea.